Synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction under catalyst-free conditions
نویسندگان
چکیده
منابع مشابه
three-component synthesis of propargylamine derivatives via 1,4-dihydroxyanthraquinone-copper(ii) complexes as an efficient catalyst under solvent-free conditions
highly active cu (ii) complex with 1,4-dihydroxy anthraquinone as a cheap and accessable ligand could be used as a catalyst for the preparation of structurally different propargylamines from a one-pot, three-component reaction of terminal alkynes, aldehydes, and secondary amines with high yields under solvent-free conditions. the 1,4-dihydroxy anthraquinone is a very efficient cu(ii) scavenger ...
متن کاملThree-component synthesis of propargylamine derivatives via 1,4-dihydroxyanthraquinone-copper(II) complexes as an efficient catalyst under solvent-free conditions
Highly active Cu (II) complex with 1,4-dihydroxy anthraquinone as a cheap and accessable ligand could be used as a catalyst for the preparation of structurally different propargylamines from a one-pot, three-component reaction of terminal alkynes, aldehydes, and secondary amines with high yields under solvent-free conditions. The 1,4-dihydroxy anthraquinone is a very efficient Cu(II) scavenger ...
متن کاملMicrowave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles
A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide-internal alkyne 1,3-dipolar cycloaddition domino sequence has been described. The efficacy of the methodology has been demonstrated by treating various 2-alkynylindoles (aromatic/aliphatic) with epichl...
متن کاملCaro’sacid-silicagel: An Efficient and Reusable Catalyst for the Synthesis of 2, 4, 5- Trisubstituted Imidazoles under Solvent-free Conditions
Caro’s acid-silicagel was found to be a mild and effective catalyst for the one –pot multicomponent condensation of benzyl, aldehydes and ammonium acetate used for synthesis of 2, 4, 5-trisubstituted imidazole derivatives under solvent–free conditions. This catalyst has several advantages such as simple work-up, low cost and reusability.
متن کاملEt3N as a catalyst for the synthesis of indeno[1,2-b]chromene derivatives via three-component condensation reaction
Functionalized indeno[1,2-b]chromene derivatives have been synthesized via condensation reaction of 1H-indene-1,3(2H)-dione with benzaldehyde and cyclization with 2-hydroxynaphthalene-1,4-dione in the presence of a catalytic amount of triethylamine (Et3N) in EtOH at room temperature. It was observed that benzaldehyde bearing electron donating group gave high yield of product, whereas, benzaldeh...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Saudi Chemical Society
سال: 2017
ISSN: 1319-6103
DOI: 10.1016/j.jscs.2016.03.001